Publisert 27.11.2017

Publication: Japan-US researchers shows pacific roe boosting collagen mRNA production in skin cells

Pacific chum salmon roe extracts show boosting of collagen I mRNA production in skin cells and induction of anti-oxidative genes.

In a recent publication in "Clinical Interventions in Aging" a team of US and Japan scientist have published new data showing that human skin fibroblasts increase mRNA for collagen I upon stimulation with "Pacific Chum Salmon" roe extracts (Clin Interv Aging,  2016 Aug 29;11:1159-68. doi: 10.2147/CIA.S102092. eCollection 2016.)

The publication confirms Regenics previously patented data on strongly increased collagen I protein production  of salmon roe extracts from atlantic salmon "Salmo Salar" in human fibroblasts.

The effect is identical to the 400-500 % collagen boosts seen both by Regenics scientists (see 2013 Fact sheet page) and verified independantly by TGA Sciences in the US for Regenics in 2016.

In addition the US-Japanese from University of  Yokohama, Tokyo and the National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA show significant upreguation of a series of anti-oxidative property genes, including OXR1, TXNRD1, and PRDX family genes. The upregulation show that  chum slamon roe ectracts excerts antioxidative effects of on human skin fibroblasts. 


Regenics AS has developed a number of assays and techniques to study effects of various substances on skin cells both in vitroin vivo and in the clinic. Our focus is to develop products and techniques for therapeutic skin applications and to improve skin appearance.