Vernex™ protective wound healing device containing a small amount of salmon roe extract. Salmon roe extract have shown a series of pre-clinical effect on ex vivo skin and skin cells that could be beneficial for wound healing.

The Vernex® device is a lipid hydrogel where the main component GMO (glycerol monooleate) provides mechanical wound protection and serves as a base for solubilizing of 2% w/v (dry weight) salmon roe extract.

GMO is a well-known and documented as biologically inert. Its commonly used in topical skin devices without having intrinsic biological effect on skin closure per se. GMO covers the wound, preserve wetness and protect the wound surface.

The final device contains 2% w/v (dry weight) of the salmon roe extract, solubilized in 90% GMO at pH 7.4. Salmon roe extract, is presumed to improve the environment in which re-epithelialization of a wound surface takes place.  This is supported by the findings in an ex-vivo human explant skin study of secondary degree burns, where the salmon roe extract is shown to increase re-epithelialization of wound surfaces compared to control. 

The prospective profile of Vernex® will support scientifically documented and patented claims:

  • VERNEX® speeds up reepitelialization of wounds
  • VERNEX® skin safety tested
  • VERNEX® causes no irritation or sensitization
  • VERNEX® delivered as hydrogel formulation
  • VERNEX® increases fibroblast migration
  • VERNEX® increases collagen synthesis
  • VERNEX® enhances hyaluronic acid secretion
  • VERNEX® increases elastin production

Regenics AS has developed a number of assays and techniques to study effects of various substances on skin cells both in vitroin vivo and in the clinic. Our focus is to develop products and techniques for therapeutic skin applications and to improve skin appearance.